eprintid: 17594
rev_number: 8
eprint_status: archive
userid: 2
dir: disk0/00/01/75/94
datestamp: 2025-04-10 23:30:12
lastmod: 2025-04-10 23:30:13
status_changed: 2025-04-10 23:30:12
type: article
metadata_visibility: show
creators_name: Martín-Rodríguez, Francisco
creators_name: Martín-Sánchez, Rafael
creators_name: del Pozo Vegas, Carlos
creators_name: Lopez-Izquierdo, Raúl
creators_name: Martín-Conty, José Luis
creators_name: Silva Alvarado, Eduardo René
creators_name: Gracia Villar, Santos
creators_name: Dzul López, Luis Alonso
creators_name: Aparicio Obregón, Silvia
creators_name: Calderón Iglesias, Rubén
creators_name: Sanz-García, Ancor
creators_name: Castro Villamor, Miguel Ángel
creators_id: 
creators_id: 
creators_id: 
creators_id: 
creators_id: 
creators_id: eduardo.silva@funiber.org
creators_id: santos.gracia@uneatlantico.es
creators_id: luis.dzul@uneatlantico.es
creators_id: silvia.aparicio@uneatlantico.es
creators_id: ruben.calderon@uneatlantico.es
creators_id: 
creators_id: 
title: Pupilometer efficacy in monitoring anxiety in undergraduate medical students during high-fidelity clinical simulation
ispublished: pub
subjects: uneat_bm
divisions: uneatlantico_produccion_cientifica
divisions: unincol_produccion_cientifica
divisions: uninimx_produccion_cientifica
divisions: uninipr_produccion_cientifica
divisions: unic_produccion_cientifica
divisions: uniromana_produccion_cientifica
full_text_status: public
keywords: Anxiety, High-fidelity clinical simulation, STAI, Pupillary diameter, Learning
abstract: The aim of the present work was to determine the correlation between the State-Trait Anxiety Inventory (STAI) score and pupillary diameter and whether this correlation exists to develop a predictive model of anxiety with the pupillary diameter of students exposed to high-fidelity clinical simulation. This was a randomized, blinded, simulation-based clinical trial. The study was conducted at the Advanced Clinical Simulation Center, Faculty of Medicine, Valladolid University (Spain), from February 1 to April 15, 2023, and involved volunteer sixth-year undergraduate medical students. The STAI score, vital signs (oxygen saturation, perfusion index, blood pressure, heart rate, and temperature), and pupillary response were assessed. The primary outcomes were the delta (pre/postsimulation) of the state STAI and the delta of the pupillary diameter. Sixty-one sixth-year students fulfilled the inclusion criteria. There was no difference regarding the clinical scenario. There was a statistically significant correlation between the state STAI score and pupillary diameter. The predictive model had an AUC of 0.876, with the delta diameter of the pupillary being the only statistically significant variable for anxiety prediction. Our results showed that both the pupillary response and the STAI score allowed the identification of students with disabling anxiety. These results could pave the way for appropriate protocol development that allows for personalized tutoring of students with elevated anxiety levels.
date: 2025-03
publication: Scientific Reports
volume: 15
number: 1
id_number: doi:10.1038/s41598-025-95290-6
refereed: TRUE
issn: 2045-2322
official_url: http://doi.org/10.1038/s41598-025-95290-6
access: open
language: en
citation:   Artículo Materias > Biomedicina <http://repositorio.unini.edu.mx/view/subjects/uneat=5Fbm.html> Universidad Europea del Atlántico > Investigación > Producción Científica <http://repositorio.unini.edu.mx/view/divisions/uneatlantico=5Fproduccion=5Fcientifica.html>
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica <http://repositorio.unini.edu.mx/view/divisions/unincol=5Fproduccion=5Fcientifica.html>
Universidad Internacional Iberoamericana México > Investigación > Artículos y libros <http://repositorio.unini.edu.mx/view/divisions/uninimx=5Fproduccion=5Fcientifica.html>
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica <http://repositorio.unini.edu.mx/view/divisions/uninipr=5Fproduccion=5Fcientifica.html>
Universidad Internacional do Cuanza > Investigación > Producción Científica <http://repositorio.unini.edu.mx/view/divisions/unic=5Fproduccion=5Fcientifica.html>
Universidad de La Romana > Investigación > Producción Científica <http://repositorio.unini.edu.mx/view/divisions/uniromana=5Fproduccion=5Fcientifica.html> Abierto Inglés The aim of the present work was to determine the correlation between the State-Trait Anxiety Inventory (STAI) score and pupillary diameter and whether this correlation exists to develop a predictive model of anxiety with the pupillary diameter of students exposed to high-fidelity clinical simulation. This was a randomized, blinded, simulation-based clinical trial. The study was conducted at the Advanced Clinical Simulation Center, Faculty of Medicine, Valladolid University (Spain), from February 1 to April 15, 2023, and involved volunteer sixth-year undergraduate medical students. The STAI score, vital signs (oxygen saturation, perfusion index, blood pressure, heart rate, and temperature), and pupillary response were assessed. The primary outcomes were the delta (pre/postsimulation) of the state STAI and the delta of the pupillary diameter. Sixty-one sixth-year students fulfilled the inclusion criteria. There was no difference regarding the clinical scenario. There was a statistically significant correlation between the state STAI score and pupillary diameter. The predictive model had an AUC of 0.876, with the delta diameter of the pupillary being the only statistically significant variable for anxiety prediction. Our results showed that both the pupillary response and the STAI score allowed the identification of students with disabling anxiety. These results could pave the way for appropriate protocol development that allows for personalized tutoring of students with elevated anxiety levels. metadata Martín-Rodríguez, Francisco; Martín-Sánchez, Rafael; del Pozo Vegas, Carlos; Lopez-Izquierdo, Raúl; Martín-Conty, José Luis; Silva Alvarado, Eduardo René; Gracia Villar, Santos; Dzul López, Luis Alonso; Aparicio Obregón, Silvia; Calderón Iglesias, Rubén; Sanz-García, Ancor y Castro Villamor, Miguel Ángel mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, eduardo.silva@funiber.org, santos.gracia@uneatlantico.es, luis.dzul@uneatlantico.es, silvia.aparicio@uneatlantico.es, ruben.calderon@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR     <http://repositorio.unini.edu.mx/id/eprint/17594/1/s41598-025-95290-6.pdf>     (2025) Pupilometer efficacy in monitoring anxiety in undergraduate medical students during high-fidelity clinical simulation.  Scientific Reports, 15 (1).   ISSN 2045-2322     
document_url: http://repositorio.unini.edu.mx/id/eprint/17594/1/s41598-025-95290-6.pdf