TY - JOUR SN - 2072-6694 VL - 14 IS - 21 AV - public ID - uninimx4611 N2 - The diagnosis of early-stage lung cancer is challenging due to its asymptomatic nature, especially given the repeated radiation exposure and high cost of computed tomography(CT). Examining the lung CT images to detect pulmonary nodules, especially the cell lung cancer lesions, is also tedious and prone to errors even by a specialist. This study proposes a cancer diagnostic model based on a deep learning-enabled support vector machine (SVM). The proposed computer-aided design (CAD) model identifies the physiological and pathological changes in the soft tissues of the cross-section in lung cancer lesions. The model is first trained to recognize lung cancer by measuring and comparing the selected profile values in CT images obtained from patients and control patients at their diagnosis. Then, the model is tested and validated using the CT scans of both patients and control patients that are not shown in the training phase. The study investigates 888 annotated CT scans from the publicly available LIDC/IDRI database. The proposed deep learning-assisted SVM-based model yields 94% accuracy for pulmonary nodule detection representing early-stage lung cancer. It is found superior to other existing methods including complex deep learning, simple machine learning, and the hybrid techniques used on lung CT images for nodule detection. Experimental results demonstrate that the proposed approach can greatly assist radiologists in detecting early lung cancer and facilitating the timely management of patients. UR - http://doi.org/10.3390/cancers14215457 TI - An Effective Method for Lung Cancer Diagnosis from CT Scan Using Deep Learning-Based Support Vector Network KW - lung cancer detection; capsule neural network; wide network; computed tomography JF - Cancers A1 - Shafi, Imran A1 - Din, Sadia A1 - Khan, Asim A1 - Díez, Isabel De La Torre A1 - Pali-Casanova, Ramón A1 - Tutusaus, Kilian A1 - Ashraf, Imran Y1 - 2022/11// ER -