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Número de registros en este nivel: 9.

2024

Artículo Materias > Ingeniería Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica
Abierto Inglés Generative intelligence relies heavily on the integration of vision and language. Much of the research has focused on image captioning, which involves describing images with meaningful sentences. Typically, when generating sentences that describe the visual content, a language model and a vision encoder are commonly employed. Because of the incorporation of object areas, properties, multi-modal connections, attentive techniques, and early fusion approaches like bidirectional encoder representations from transformers (BERT), these components have experienced substantial advancements over the years. This research offers a reference to the body of literature, identifies emerging trends in an area that blends computer vision as well as natural language processing in order to maximize their complementary effects, and identifies the most significant technological improvements in architectures employed for image captioning. It also discusses various problem variants and open challenges. This comparison allows for an objective assessment of different techniques, architectures, and training strategies by identifying the most significant technical innovations, and offers valuable insights into the current landscape of image captioning research. metadata Jamil, Azhar; Rehman, Saif Ur; Mahmood, Khalid; Gracia Villar, Mónica; Prola, Thomas; Diez, Isabel De La Torre; Samad, Md Abdus y Ashraf, Imran mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, monica.gracia@uneatlantico.es, thomas.prola@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR (2024) Deep Learning Approaches for Image Captioning: Opportunities, Challenges and Future Potential. IEEE Access. p. 1. ISSN 2169-3536

Artículo Materias > Biomedicina
Materias > Alimentación
Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica
Abierto Inglés Isoflavones are a group of (poly)phenols, also defined as phytoestrogens, with chemical structures comparable with estrogen, that exert weak estrogenic effects. These phytochemical compounds have been targeted for their proven antioxidant and protective effects. Recognizing the increasing prevalence of cardiovascular diseases (CVD), there is a growing interest in understanding the potential cardiovascular benefits associated with these phytochemical compounds. Gut microbiota may play a key role in mediating the effects of isoflavones on vascular and endothelial functions, as it is directly implicated in isoflavones metabolism. The findings from randomized clinical trials indicate that isoflavone supplementation may exert putative effects on vascular biomarkers among healthy individuals, but not among patients affected by cardiometabolic disorders. These results might be explained by the enzymatic transformation to which isoflavones are subjected by the gut microbiota, suggesting that a diverse composition of the microbiota may determine the diverse bioavailability of these compounds. Specifically, the conversion of isoflavones in equol—a microbiota-derived metabolite—seems to differ between individuals. Further studies are needed to clarify the intricate molecular mechanisms behind these contrasting results. metadata Laudani, Samuele; Godos, Justyna; Romano, Giovanni Luca; Gozzo, Lucia; Di Domenico, Federica Martina; Dominguez Azpíroz, Irma; Martínez Díaz, Raquel; Giampieri, Francesca; Quiles, José L.; Battino, Maurizio; Drago, Filippo; Galvano, Fabio y Grosso, Giuseppe mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, irma.dominguez@unini.edu.mx, raquel.martinez@uneatlantico.es, francesca.giampieri@uneatlantico.es, jose.quiles@uneatlantico.es, maurizio.battino@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR (2024) Isoflavones Effects on Vascular and Endothelial Outcomes: How Is the Gut Microbiota Involved? Pharmaceuticals, 17 (2). p. 236. ISSN 1424-8247

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica
Abierto Inglés The prevalence of sleep disorders, characterized by issues with quality, timing, and sleep duration is increasing globally. Among modifiable risk factors, diet quality has been suggested to influence sleep features. The Mediterranean diet is considered a landmark dietary pattern in terms of quality and effects on human health. However, dietary habits characterized by this cultural heritage should also be considered in the context of overall lifestyle behaviors, including sleep habits. This study aimed to systematically revise the literature relating to adherence to the Mediterranean diet and sleep features in observational studies. The systematic review comprised 23 reports describing the relation between adherence to the Mediterranean diet and different sleep features, including sleep quality, sleep duration, daytime sleepiness, and insomnia symptoms. The majority of the included studies were conducted in the Mediterranean basin and reported a significant association between a higher adherence to the Mediterranean diet and a lower likelihood of having poor sleep quality, inadequate sleep duration, excessive daytime sleepiness or symptoms of insomnia. Interestingly, additional studies conducted outside the Mediterranean basin showed a relationship between the adoption of a Mediterranean-type diet and sleep quality, suggesting that biological mechanisms sustaining such an association may exist. In conclusion, current evidence suggests a relationship between adhering to the Mediterranean diet and overall sleep quality and different sleep parameters. The plausible bidirectional association should be further investigated to understand whether the promotion of a healthy diet could be used as a tool to improve sleep quality. metadata Godos, Justyna; Ferri, Raffaele; Lanza, Giuseppe; Caraci, Filippo; Rojas Vistorte, Angel Olider; Yélamos Torres, Vanessa; Grosso, Giuseppe y Castellano, Sabrina mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, angel.rojas@uneatlantico.es, vanessa.yelamos@funiber.org, SIN ESPECIFICAR, SIN ESPECIFICAR (2024) Mediterranean Diet and Sleep Features: A Systematic Review of Current Evidence. Nutrients, 16 (2). p. 282. ISSN 2072-6643

2023

Artículo Materias > Ingeniería Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica
Abierto Inglés Behavioral economics and artificial intelligence (AI) have been two rapidly growing fields of research over the past few years. While behavioral economics aims to combine concepts from psychology, sociology, and neuroscience with classical economic thoughts to understand human decision-making processes in the complex economic environment, AI on the other hand, focuses on creating intelligent machines that can mimic human cognitive abilities such as learning, problem-solving, decision-making, and language understanding. The intersection of these two fields has led to thrilling research theories and practical applications. This study provides a bibliometric analysis of the literature on AI and behavioral economics to gain insight into research trends in this field. We conducted this bibliometric analysis using the Web of Science database on articles published between 2012 and 2022 that were related to AI and behavioral economics. VOSviewer and Bibliometrix R package were utilized to identify influential authors, journals, institutions, and countries in the field. Network analysis was also performed to identify the main research themes and their interrelationships. The analysis revealed that the number of publications on AI and behavioral economics has been increasing steadily over the past decade. We found that most studies focused on customer and consumer behavior, including topics such as decision-making under uncertainty, neuroeconomics, and behavioral game theory, combined mainly with machine learning and deep learning techniques. We also identified several emerging themes, including the use of AI in nudging and prospect theory in behavioral finance, as well as undeveloped themes such as AI-driven behavioral macroeconomics. The findings suggests that there is a need for more interdisciplinary collaboration between researchers in behavioral economics and AI. We also suggest that future research on AI and behavioral economics further consider the ethical implications of using AI and behavioral insights in decision-making. This study can serve as a valuable resource for researchers interested in AI and behavioral economics. metadata Aoujil, Zakaria; Hanine, Mohamed; Soriano Flores, Emmanuel; Samad, Md Abdu y Ashraf, Imran mail SIN ESPECIFICAR, SIN ESPECIFICAR, emmanuel.soriano@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR (2023) Artificial Intelligence and Behavioral Economics: A Bibliographic Analysis of Research Field. IEEE Access. p. 1. ISSN 2169-3536 (En Prensa)

Artículo Materias > Biomedicina Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica
Abierto Inglés Objective The aim was to explore the association of demographic and prehospital parameters with short-term and long-term mortality in acute life-threatening cardiovascular disease by using a hazard model, focusing on elderly individuals, by comparing patients under 75 years versus patients over 75 years of age. Design Prospective, multicentre, observational study. Setting Emergency medical services (EMS) delivery study gathering data from two back-to-back studies between 1 October 2019 and 30 November 2021. Six advanced life support (ALS), 43 basic life support and five hospitals in Spain were considered. Participants Adult patients suffering from acute life-threatening cardiovascular disease attended by the EMS. Primary and secondary outcome measures The primary outcome was in-hospital mortality from any cause within the first to the 365 days following EMS attendance. The main measures included prehospital demographics, biochemical variables, prehospital ALS techniques used and syndromic suspected conditions. Results A total of 1744 patients fulfilled the inclusion criteria. The 365-day cumulative mortality in the elderly amounted to 26.1% (229 cases) versus 11.6% (11.6%) in patients under 75 years old. Elderly patients (≥75 years) presented a twofold risk of mortality compared with patients ≤74 years. Life-threatening interventions (mechanical ventilation, cardioversion and defibrillation) were also related to a twofold increased risk of mortality. Importantly, patients suffering from acute heart failure presented a more than twofold increased risk of mortality. Conclusions This study revealed the prehospital variables associated with the long-term mortality of patients suffering from acute cardiovascular disease. Our results provide important insights for the development of specific codes or scores for cardiovascular diseases to facilitate the risk of mortality characterisation. metadata del Pozo Vegas, Carlos; Zalama-Sánchez, Daniel; Sanz-Garcia, Ancor; López-Izquierdo, Raúl; Sáez-Belloso, Silvia; Mazas Pérez-Oleaga, Cristina; Dominguez Azpíroz, Irma; Elío Pascual, Iñaki y Martín-Rodríguez, Francisco mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, cristina.mazas@uneatlantico.es, irma.dominguez@unini.edu.mx, inaki.elio@uneatlantico.es, SIN ESPECIFICAR (2023) Prehospital acute life-threatening cardiovascular disease in elderly: an observational, prospective, multicentre, ambulance-based cohort study. BMJ Open, 13 (11). e078815. ISSN 2044-6055

Artículo Materias > Biomedicina Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica
Abierto Inglés Introduction: Rotavirus infection is a major cause of mortality among children under 5 years in Bangladesh. There is lack of integrated studies on rotavirus prevalence and genetic diversity during 1973 to 2023 in Bangladesh. Methods: This meta-analysis was conducted to determine the prevalence, genotypic diversity and seasonal distribution of rotavirus during pre-vaccination period in Bangladesh. This study included published articles on rotavirus A, rotavirus B and rotavirus C. We used Medline, Scopus and Google Scholar for published articles. Selected literatures were published between 1973 to 2023. Results: This study detected 12431 research articles published on rotavirus. Based on the inclusion criteria, 29 of 75 (30.2%) studies were selected. Molecular epidemiological data was taken from 29 articles, prevalence data from 29 articles, and clinical symptoms from 19 articles. The pooled prevalence of rotavirus was 30.1% (95% CI: 22%-45%, p = 0.005). Rotavirus G1 (27.1%, 2228 of 8219) was the most prevalent followed by G2 (21.09%, 1733 of 8219), G4 (11.58%, 952 of 8219), G9 (9.37%, 770 of 8219), G12 (8.48%, 697 of 8219), and G3 (2.79%, 229 of 8219), respectively. Genotype P[8] (40.6%, 2548 of 6274) was the most prevalent followed by P[4] (12.4%, 777 of 6274) and P[6] (6.4%, 400 of 6274), respectively. Rotavirus G1P[8] (19%) was the most frequent followed by G2P [4] (9.4%), G12P[8] (7.2%), and G9P[8], respectively. Rotavirus infection had higher odds of occurrence during December and February (aOR: 2.86, 95% CI: 2.43-3.6, p = 0.001). Discussion: This is the first meta-analysis including all the studies on prevalence, molecular epidemiology, and genetic diversity of rotavirus from 1973 to 2023, pre-vaccination period in Bangladesh. This study will provide overall scenario of rotavirus genetic diversity and seasonality during pre-vaccination period and aids in policy making for rotavirus vaccination program in Bangladesh. This work will add valuable knowledge for vaccination against rotavirus and compare the data after starting vaccination in Bangladesh. metadata Sharif, Nadim; Sharif, Nazmul; Khan, Afsana; Dominguez Azpíroz, Irma; Martínez Díaz, Raquel; Díez, Isabel De la Torre; Parvez, Anowar Khasru y Dey, Shuvra Kanti mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, irma.dominguez@unini.edu.mx, raquel.martinez@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR (2023) Prevalence and genetic diversity of rotavirus in Bangladesh during pre-vaccination period, 1973-2023: a meta-analysis. Frontiers in Immunology, 14. ISSN 1664-3224

Artículo Materias > Ingeniería Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica
Abierto Inglés Software cost and effort estimation is one of the most significant tasks in the area of software engineering. Research conducted in this field has been evolving with new techniques that necessitate periodic comparative analyses. Software project success largely depends on accurate software cost estimation as it gives an idea of the challenges and risks involved in the development. The great diversity of ML and Non-ML techniques has generated a comparison and progressed into the integration of these techniques. Based on varying advantages it has become imperative to work out preferred estimation techniques to improve the project development process. This study aims to present a systematic literature review (SLR) to investigate the trends of the articles published in the recent one and a half decades and to propose a way forward. This systematic literature review has proposed a three-stage approach to plan (Tollgate approach), conduct (Likert type scale), and report the results from five renowned digital libraries. For the selected 52 articles, artificial neural network model (ANN) and constructive cost model (COCOMO) based approaches have been the favored techniques. The mean magnitude of relative error (MMRE) has been the preferred accuracy metric, software engineering, and project management are the most relevant fields, and the promise repository has been identified as the widely accessed database. This review is likely to be of value for the development, cost, and effort estimations. metadata Rashid, Chaudhary Hamza; Shafi, Imran; Ahmad, Jamil; Bautista Thompson, Ernesto; Masías Vergara, Manuel; Diez, Isabel De La Torre y Ashraf, Imran mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, ernesto.bautista@unini.edu.mx, manuel.masias@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR (2023) Software Cost and Effort Estimation: Current Approaches and Future Trends. IEEE Access. p. 1. ISSN 2169-3536

Artículo Materias > Ingeniería Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica
Abierto Inglés Data mining is an analytical approach that contributes to achieving a solution to many problems by extracting previously unknown, fascinating, nontrivial, and potentially valuable information from massive datasets. Clustering in data mining is used for splitting or segmenting data items/points into meaningful groups and clusters by grouping the items that are near to each other based on certain statistics. This paper covers various elements of clustering, such as algorithmic methodologies, applications, clustering assessment measurement, and researcher-proposed enhancements with their impact on data mining thorough grasp of clustering algorithms, its applications, and the advances achieved in the existing literature. This study includes a literature search for papers published between 1995 and 2023, including conference and journal publications. The study begins by outlining fundamental clustering techniques along with algorithm improvements and emphasizing their advantages and limitations in comparison to other clustering algorithms. It investigates the evolution measures for clustering algorithms with an emphasis on metrics used to gauge clustering quality, such as the F-measure and the Rand Index. This study includes a variety of clustering-related topics, such as algorithmic approaches, practical applications, metrics for clustering evaluation, and researcher-proposed improvements. It addresses numerous methodologies offered to increase the convergence speed, resilience, and accuracy of clustering, such as initialization procedures, distance measures, and optimization strategies. The work concludes by emphasizing clustering as an active research area driven by the need to identify significant patterns and structures in data, enhance knowledge acquisition, and improve decision making across different domains. This study aims to contribute to the broader knowledge base of data mining practitioners and researchers, facilitating informed decision making and fostering advancements in the field through a thorough analysis of algorithmic enhancements, clustering assessment metrics, and optimization strategies. metadata Chaudhry, Mahnoor; Shafi, Imran; Mahnoor, Mahnoor; Ramírez-Vargas, Debora L.; Bautista Thompson, Ernesto y Ashraf, Imran mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, debora.ramirez@unini.edu.mx, ernesto.bautista@unini.edu.mx, SIN ESPECIFICAR (2023) A Systematic Literature Review on Identifying Patterns Using Unsupervised Clustering Algorithms: A Data Mining Perspective. Symmetry, 15 (9). p. 1679. ISSN 2073-8994

Artículo Materias > Ingeniería Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica
Abierto Inglés Artificial intelligence (AI)-based models have emerged as powerful tools in financial markets, capable of reducing investment risks and aiding in selecting highly profitable stocks by achieving precise predictions. This holds immense value for investors, as it empowers them to make data-driven decisions. Identifying current and future trends in multi-class forecasting techniques employed within financial markets, particularly profitability analysis as an evaluation metric is important. The review focuses on examining stud-ies conducted between 2018 and 2023, sourced from three prominent academic databases. A meticulous three-stage approach was employed, encompassing the systematic planning, conduct, and analysis of the se-lected studies. Specifically, the analysis emphasizes technical assessment, profitability analysis, hybrid mod-eling, and the type of results generated by models. Articles were shortlisted based on inclusion and exclusion criteria, while a rigorous quality assessment through ten quality criteria questions, utilizing a Likert-type scale was employed to ensure methodological robustness. We observed that ensemble and hybrid models with long short-term memory (LSTM) and support vector machines (SVM) are being more adopted for financial trends and price prediction. Moreover, hybrid models employing AI algorithms for feature engineering have great potential at par with ensemble techniques. Most studies only employ performance metrics and lack utilization of profitability metrics or investment or trading strategy (simulated or real-time). Similarly, research on multi-class or output is severely lacking in financial forecasting and can be a good avenue for future research. metadata Khattak, Bilal Hassan Ahmed; Shafi, Imran; Khan, Abdul Saboor; Soriano Flores, Emmanuel; García Lara, Roberto; Samad, Md. Abdus y Ashraf, Imran mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, emmanuel.soriano@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR (2023) A Systematic Survey of AI Models in Financial Market Forecasting for Profitability Analysis. IEEE Access, 11. pp. 125359-125380. ISSN 2169-3536

<a class="ep_document_link" href="/10290/1/Influence%20of%20E-learning%20training%20on%20the%20acquisition%20of%20competences%20in%20basketball%20coaches%20in%20Cantabria.pdf"><img class="ep_doc_icon" alt="[img]" src="/style/images/fileicons/text.png" border="0"/></a>

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Influence of E-learning training on the acquisition of competences in basketball coaches in Cantabria

The main aim of this study was to analyse the influence of e-learning training on the acquisition of competences in basketball coaches in Cantabria. The current landscape of basketball coach training shows an increasing demand for innovative training models and emerging pedagogies, including e-learning-based methodologies. The study sample consisted of fifty students from these courses, all above 16 years of age (36 males, 14 females). Among them, 16% resided outside the autonomous community of Cantabria, 10% resided more than 50 km from the city of Santander, 36% between 10 and 50 km, 14% less than 10 km, and 24% resided within Santander city. Data were collected through a Google Forms survey distributed by the Cantabrian Basketball Federation to training course students. Participation was voluntary and anonymous. The survey, consisting of 56 questions, was validated by two sports and health doctors and two senior basketball coaches. The collected data were processed and analysed using Microsoft® Excel version 16.74, and the results were expressed in percentages. The analysis revealed that 24.60% of the students trained through the e-learning methodology considered themselves fully qualified as basketball coaches, contrasting with 10.98% of those trained via traditional face-to-face methodology. The results of the study provide insights into important characteristics that can be adjusted and improved within the investigated educational process. Moreover, the study concludes that e-learning training effectively qualifies basketball coaches in Cantabria.

Producción Científica

Josep Alemany Iturriaga mail josep.alemany@uneatlantico.es, Álvaro Velarde-Sotres mail alvaro.velarde@uneatlantico.es, Javier Jorge mail , Kamil Giglio mail ,

Alemany Iturriaga

<a class="ep_document_link" href="/11642/1/s41598-024-57547-4.pdf"><img class="ep_doc_icon" alt="[img]" src="/style/images/fileicons/text.png" border="0"/></a>

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Adaptive neighborhood rough set model for hybrid data processing: a case study on Parkinson’s disease behavioral analysis

Extracting knowledge from hybrid data, comprising both categorical and numerical data, poses significant challenges due to the inherent difficulty in preserving information and practical meanings during the conversion process. To address this challenge, hybrid data processing methods, combining complementary rough sets, have emerged as a promising approach for handling uncertainty. However, selecting an appropriate model and effectively utilizing it in data mining requires a thorough qualitative and quantitative comparison of existing hybrid data processing models. This research aims to contribute to the analysis of hybrid data processing models based on neighborhood rough sets by investigating the inherent relationships among these models. We propose a generic neighborhood rough set-based hybrid model specifically designed for processing hybrid data, thereby enhancing the efficacy of the data mining process without resorting to discretization and avoiding information loss or practical meaning degradation in datasets. The proposed scheme dynamically adapts the threshold value for the neighborhood approximation space according to the characteristics of the given datasets, ensuring optimal performance without sacrificing accuracy. To evaluate the effectiveness of the proposed scheme, we develop a testbed tailored for Parkinson’s patients, a domain where hybrid data processing is particularly relevant. The experimental results demonstrate that the proposed scheme consistently outperforms existing schemes in adaptively handling both numerical and categorical data, achieving an impressive accuracy of 95% on the Parkinson’s dataset. Overall, this research contributes to advancing hybrid data processing techniques by providing a robust and adaptive solution that addresses the challenges associated with handling hybrid data, particularly in the context of Parkinson’s disease analysis.

Producción Científica

Imran Raza mail , Muhammad Hasan Jamal mail , Rizwan Qureshi mail , Abdul Karim Shahid mail , Angel Olider Rojas Vistorte mail angel.rojas@uneatlantico.es, Md Abdus Samad mail , Imran Ashraf mail ,

Raza

<a class="ep_document_link" href="/11265/1/Food%20Frontiers%20-%202024%20-%20Cassotta%20-%20Human%E2%80%90based%20new%20approach%20methodologies%20to%20accelerate%20advances%20in%20nutrition%20research.pdf"><img class="ep_doc_icon" alt="[img]" src="/style/images/fileicons/text.png" border="0"/></a>

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Human‐based new approach methodologies to accelerate advances in nutrition research

Much of nutrition research has been conventionally based on the use of simplistic in vitro systems or animal models, which have been extensively employed in an effort to better understand the relationships between diet and complex diseases as well as to evaluate food safety. Although these models have undeniably contributed to increase our mechanistic understanding of basic biological processes, they do not adequately model complex human physiopathological phenomena, creating concerns about the translatability to humans. During the last decade, extraordinary advancement in stem cell culturing, three-dimensional cell cultures, sequencing technologies, and computer science has occurred, which has originated a wealth of novel human-based and more physiologically relevant tools. These tools, also known as “new approach methodologies,” which comprise patient-derived organoids, organs-on-chip, multi-omics approach, along with computational models and analysis, represent innovative and exciting tools to forward nutrition research from a human-biology-oriented perspective. After considering some shortcomings of conventional in vitro and vivo approaches, here we describe the main novel available and emerging tools that are appropriate for designing a more human-relevant nutrition research. Our aim is to encourage discussion on the opportunity to explore innovative paths in nutrition research and to promote a paradigm-change toward a more human biology-focused approach to better understand human nutritional pathophysiology, to evaluate novel food products, and to develop more effective targeted preventive or therapeutic strategies while helping in reducing the number and replacing animals employed in nutrition research.

Producción Científica

Manuela Cassotta mail manucassotta@gmail.com, Danila Cianciosi mail , Maria Elexpuru Zabaleta mail maria.elexpuru@uneatlantico.es, Iñaki Elío Pascual mail inaki.elio@uneatlantico.es, Sandra Sumalla Cano mail sandra.sumalla@uneatlantico.es, Francesca Giampieri mail francesca.giampieri@uneatlantico.es, Maurizio Battino mail maurizio.battino@uneatlantico.es,

Cassotta

<a class="ep_document_link" href="/11322/1/journal.pone.0298582.pdf"><img class="ep_doc_icon" alt="[img]" src="/style/images/fileicons/text.png" border="0"/></a>

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Design and development of patient health tracking, monitoring and big data storage using Internet of Things and real time cloud computing

With the outbreak of the COVID-19 pandemic, social isolation and quarantine have become commonplace across the world. IoT health monitoring solutions eliminate the need for regular doctor visits and interactions among patients and medical personnel. Many patients in wards or intensive care units require continuous monitoring of their health. Continuous patient monitoring is a hectic practice in hospitals with limited staff; in a pandemic situation like COVID-19, it becomes much more difficult practice when hospitals are working at full capacity and there is still a risk of medical workers being infected. In this study, we propose an Internet of Things (IoT)-based patient health monitoring system that collects real-time data on important health indicators such as pulse rate, blood oxygen saturation, and body temperature but can be expanded to include more parameters. Our system is comprised of a hardware component that collects and transmits data from sensors to a cloud-based storage system, where it can be accessed and analyzed by healthcare specialists. The ESP-32 microcontroller interfaces with the multiple sensors and wirelessly transmits the collected data to the cloud storage system. A pulse oximeter is utilized in our system to measure blood oxygen saturation and body temperature, as well as a heart rate monitor to measure pulse rate. A web-based interface is also implemented, allowing healthcare practitioners to access and visualize the collected data in real-time, making remote patient monitoring easier. Overall, our IoT-based patient health monitoring system represents a significant advancement in remote patient monitoring, allowing healthcare practitioners to access real-time data on important health metrics and detect potential health issues before they escalate.

Producción Científica

Md. Milon Islam mail , Imran Shafi mail , Sadia Din mail , Siddique Farooq mail , Isabel de la Torre Díez mail , Jose Breñosa mail josemanuel.brenosa@uneatlantico.es, Julio César Martínez Espinosa mail ulio.martinez@unini.edu.mx, Imran Ashraf mail ,

Islam

<a href="/11324/1/navarro-hortal-et-al-2024-in-vitro-and-in-vivo-insights-into-a-broccoli-byproduct-as-a-healthy-ingredient-for-the.pdf" class="ep_document_link"><img class="ep_doc_icon" alt="[img]" src="/style/images/fileicons/text.png" border="0"/></a>

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In Vitro and In Vivo Insights into a Broccoli Byproduct as a Healthy Ingredient for the Management of Alzheimer’s Disease and Aging through Redox Biology

Broccoli has gained popularity as a highly consumed vegetable due to its nutritional and health properties. This study aimed to evaluate the composition profile and the antioxidant capacity of a hydrophilic extract derived from broccoli byproducts, as well as its influence on redox biology, Alzheimer’s disease markers, and aging in the Caenorhabditis elegans model. The presence of glucosinolate was observed and antioxidant capacity was demonstrated both in vitro and in vivo. The in vitro acetylcholinesterase inhibitory capacity was quantified, and the treatment ameliorated the amyloid-β- and tau-induced proteotoxicity in transgenic strains via SOD-3 and SKN-1, respectively, and HSP-16.2 for both parameters. Furthermore, a preliminary study on aging indicated that the extract effectively reduced reactive oxygen species levels in aged worms and extended their lifespan. Utilizing broccoli byproducts for nutraceutical or functional foods could manage vegetable processing waste, enhancing productivity and sustainability while providing significant health benefits.

Producción Científica

María D. Navarro-Hortal mail , Jose M. Romero-Márquez mail , M. Asunción López-Bascón mail , Cristina Sánchez-González mail , Jianbo Xiao mail , Sandra Sumalla Cano mail sandra.sumalla@uneatlantico.es, Maurizio Battino mail maurizio.battino@uneatlantico.es, Tamara Y. Forbes-Hernande mail tamara.forbes@unini.edu.mx, José L. Quiles mail jose.quiles@uneatlantico.es,

Navarro-Hortal