Documentos donde el Autor es "Godos, Justyna"

Artículo Materias > Biomedicina
Materias > Alimentación Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Artículos y libros
Universidad Internacional do Cuanza > Investigación > Producción Científica Abierto Inglés Background Age-related structural changes in the human brain, including cortical atrophy, reductions in grey and white matter volumes, and the accumulation of small vessel–related lesions such as white matter hyperintensities (WMH) and cerebral microbleeds, represent critical biological substrates underlying cognitive decline and dementia. Fish consumption has been associated with slower cognitive decline and reduced risk of dementia, but a comprehensive evaluation of its relation with brain structures is lacking. Aims The aim of this study was to systematically review current scientific literature providing evidence of relation between fish intake and brain structures in human studies. Methods Studies indexed in two major electronic databases have been screened based on a combination of keywords and MeSH terms. Studies were eligible whether they assessed fish consumption in relation to brain structures in the adult populations. Results A total of 24 studies conducted predominantly on older adults met inclusion criteria. Most brain volume measures were obtained via magnetic resonance imaging (MRI) procedures. Higher fish consumption was associated with reduced severity of white matter hyperintensities (a biomarker of cerebral small vessel disease and white matter damage) and cerebral micro-bleed, preservation of certain brain areas volumes (i.e., hippocampus, temporal lobe and periventricle white matter) and cortical thickness of specific areas (i.e., precuneus, parietal, and cingulate grey matter), among others, compared to lower intake. Some analyses found no association and isolated findings suggested possible adverse associations that were not consistently replicated. Studies reporting null findings may underline the possible relevance of the overall diet (i.e., adherence to the Mediterranean diet). Conclusions Inclusion of fish in a healthy and balanced diet is associated with better white matter grades on MRI and slower progression of white matter hyperintensities and reduction of vascular-related lesions of the aging brain, suggesting a potential role in preventing neurocognitive deterioration. Heterogeneity across studies underscores the need for additional studies. metadata Godos, Justyna; Caruso, Giuseppe; Micek, Agnieszka; Dolci, Alberto; Ungvari, Zoltan; Lehoczki, Andrea; León Brizuela, Lisandra; Frias-Toral, Evelyn; Di Mauro, Andrea; Siervo, Mario; Di Rosa, Michelino y Grosso, Giuseppe mail SIN ESPECIFICAR (2026) Fish consumption and brain structure: a comprehensive systematic review of observational studies. Aging Clinical and Experimental Research. ISSN 1720-8319

Artículo Materias > Biomedicina
Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Artículos y libros
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica Abierto Inglés Polyphenols are naturally occurring compounds that can be found in plant-based foods, including fruits, vegetables, nuts, seeds, herbs, spices, and beverages, the use of which has been linked to enhanced brain health and cognitive function. These natural molecules are broadly classified into two main groups: flavonoids and non-flavonoid polyphenols, the latter including phenolic acids, stilbenes, and tannins. Flavonoids are primarily known for their potent antioxidant properties, which help neutralize harmful reactive oxygen species (ROS) in the brain, thereby reducing oxidative stress, a key contributor to neurodegenerative diseases. In addition to their antioxidant effects, flavonoids have been shown to modulate inflammation, enhance neuronal survival, and support neurogenesis, all of which are critical for maintaining cognitive function. Phenolic acids possess strong antioxidant properties and are believed to protect brain cells from oxidative damage. Neuroprotective effects of these molecules can also depend on their ability to modulate signaling pathways associated with inflammation and neuronal apoptosis. Among polyphenols, hydroxycinnamic acids such as caffeic acid have been shown to enhance blood-brain barrier permeability, which may increase the delivery of other protective compounds to the brain. Another compound of interest is represented by resveratrol, a stilbene extensively studied for its potential neuroprotective properties related to its ability to activate the sirtuin pathway, a molecular signaling pathway involved in cellular stress response and aging. Lignans, on the other hand, have shown promise in reducing neuroinflammation and oxidative stress, which could help slow the progression of neurodegenerative diseases and cognitive decline. Polyphenols belonging to different subclasses, such as flavonoids, phenolic acids, stilbenes, and lignans, exert neuroprotective effects by regulating microglial activation, suppressing pro-inflammatory cytokines, and mitigating oxidative stress. These compounds act through multiple signaling pathways, including NF-κB, MAPK, and Nrf2, and they may also influence genetic regulation of inflammation and immune responses at brain level. Despite their potential for brain health and cognitive function, polyphenols are often characterized by low bioavailability, something that deserves attention when considering their therapeutic potential. Future translational studies are needed to better understand the right dosage, the overall diet, the correct target population, as well as ideal formulations allowing to overcome bioavailability limitations. metadata Godos, Justyna; Carota, Giuseppe; Caruso, Giuseppe; Micek, Agnieszka; Frias-Toral, Evelyn; Giampieri, Francesca; Brito Ballester, Julién; Battino, Maurizio; Rodríguez Velasco, Carmen Lilí y Quiles, José L. mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, francesca.giampieri@uneatlantico.es, julien.brito@uneatlantico.es, maurizio.battino@uneatlantico.es, carmen.rodriguez@uneatlantico.es, jose.quiles@uneatlantico.es (2025) Molecular mechanisms underlying the neuroprotective effects of polyphenols: implications for cognitive function. EXCLI journal, 24. pp. 1262-1294. ISSN 1611-2156

Artículo Materias > Biomedicina Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Artículos y libros
Universidad Internacional do Cuanza > Investigación > Producción Científica Cerrado Inglés The intake of anthocyanins has been shown to have significant effects on the gut microbiota, influencing its composition, diversity, and functionality. These effects include promoting the growth of beneficial bacterial families, such as Bifidobacterium and Lactobacillus, and ameliorating microbiota diversity. The specific enzymes produced by these bacteria, such as β-glucosidases, hydrolases, and decarboxylases, are crucial for breaking down complex anthocyanin structures and converting them into bioactive molecules, able to cross the blood-brain barrier, potentially affecting brain health. As more research is needed into the specific roles of different microbial species on metabolites production, it becomes increasingly clear that the gut microbiota may play an important role in unlocking the potential health benefits of anthocyanins also in relation to brain health. metadata Godos, Justyna; Micek, Agnieszka; Caruso, Giuseppe; Carota, Giuseppe; Di Mauro, Andrea; Furnari, Fabrizio; Di Giorgio, Jason; D’Agostino, Martina; Leonardi, Alice; Balzano, Rosa MG; Di Venuta, Christian; Giampieri, Francesca; Alemany Iturriaga, Josep; Torrisi, Sebastiano Alfio; Leggio, Gian Marco y Grosso, Giuseppe mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, francesca.giampieri@uneatlantico.es, josep.alemany@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR (2025) Anthocyanin metabolites from gut microbiota and cognitive health. Journal of Berry Research, 15 (4). pp. 239-248. ISSN 1878-5093

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Artículos y libros
Universidad Internacional do Cuanza > Investigación > Producción Científica Abierto Inglés Background/Objectives: Sleep is a fundamental physiological function that plays a crucial role in maintaining health and well-being. The aim of this study was to assess dietary and lifestyle factors associated with adequate sleep duration in children and adolescents living in five Mediterranean countries. Methods: Parents of children and adolescents taking part in an initial survey for the DELICIOUS project were examined to assess their children’s dietary and eating habits (i.e., meal routines), as well as other lifestyle behaviors (i.e., physical activity levels, screen time, etc.) potentially associated with adequate sleep duration (defined as 8–10 h according to the National Sleep Foundation). The youth healthy eating index (Y-HEI) was used to assess the diet quality of children and adolescents. Multivariate logistic regression analyses were performed to calculate the odds ratios (ORs) and 95% confidence intervals (CIs), indicating the level of association between variables. Results: A total of 2011 individuals participated in the survey. The adolescents and children of younger parents reported being more likely to have inadequate sleep duration. Among eating behaviors, having breakfast (OR = 2.23, 95% CI: 1.62, 3.08) and eating at school (OR = 1.33, 95% CI: 1.01, 1.74) were associated with adequate sleep duration. In contrast, children eating alone, screen time, and eating outside of the home were less likely to have adequate sleep duration, although these findings were only significant in the unadjusted model. After adjusting for covariates, a better diet quality (OR = 1.63, 95% CI: 1.24, 2.16), including higher intake of fruits, meat, fish, and whole grains, was associated with adequate sleep duration. Conclusions: Adequate sleep duration seems to be highly influenced by factors related to individual lifestyles, family and school eating behaviors, as well as diet quality. metadata Godos, Justyna; Rosi, Alice; Scazzina, Francesca; Touriz Bonifaz, Maria Antonieta; Giampieri, Francesca; Abdelkarim, Osama; Ammar, Achraf; Aly, Mohamed; Frias-Toral, Evelyn; Pons, Juancho; Vázquez-Araújo, Laura; Alemany Iturriaga, Josep; Monasta, Lorenzo; Mata, Ana; Chacón, Adrián; Busó, Pablo y Grosso, Giuseppe mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, francesca.giampieri@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, josep.alemany@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR (2025) Diet, Eating Habits, and Lifestyle Factors Associated with Adequate Sleep Duration in Children and Adolescents Living in 5 Mediterranean Countries: The DELICIOUS Project. Nutrients, 17 (7). p. 1242. ISSN 2072-6643

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Artículos y libros
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica Abierto Inglés Background/Objectives: With the increasing life expectancy and, as a result, the aging of the global population, there has been a rise in the prevalence of chronic conditions, which can significantly impact individuals’ health-related quality of life, a multidimensional concept that comprises an individual’s physical, mental, and social wellbeing. While a balanced, nutrient-dense diet, such as Mediterranean diet, is widely recognized for its role in chronic disease prevention, particularly in reducing the risk of cardiovascular diseases and certain cancers, its potential benefits extend beyond these well-known effects, showing promise in improving physical and mental wellbeing, and promoting health-related quality of life. Methods: A systematic search of the scientific literature in electronic databases (Pubmed/Medline) was performed to identify potentially eligible studies reporting on the relation between adherence to the Mediterranean diet and health-related quality of life, published up to December 2024. Results: A total of 28 studies were included in this systematic review, comprising 13 studies conducted among the general population and 15 studies involving various types of patients. Overall, most studies showed a significant association between adherence to the Mediterranean diet and HRQoL, with the most significant results retrieved for physical domains of quality of life, suggesting that diet seems to play a relevant role in both the general population and people affected by chronic conditions with an inflammatory basis. Conclusions: Adherence to the Mediterranean diet provides significant benefits in preventing and managing various chronic diseases commonly associated with aging populations. Furthermore, it enhances the overall health and quality of life of aging individuals, ultimately supporting more effective and less invasive treatment approaches for chronic diseases. metadata Godos, Justyna; Guglielmetti, Monica; Ferraris, Cinzia; Frias-Toral, Evelyn; Dominguez Azpíroz, Irma; Lipari, Vivian; Di Mauro, Andrea; Furnari, Fabrizio; Castellano, Sabrina; Galvano, Fabio; Iacoviello, Licia; Bonaccio, Marialaura y Grosso, Giuseppe mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, irma.dominguez@unini.edu.mx, vivian.lipari@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR (2025) Mediterranean Diet and Quality of Life in Adults: A Systematic Review. Nutrients, 17 (3). p. 577. ISSN 2072-6643

Artículo Materias > Biomedicina
Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Artículos y libros
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica Abierto Inglés Fasting–feeding timing is a crucial pattern implicated in the regulation of daily circadian rhythms. The interplay between sleep and meal timing underscores the importance of maintaining circadian alignment in order to avoid creating a metabolic environment conducive to carcinogenesis following the molecular and systemic disruption of metabolic performance and immune function. The chronicity of such a condition may support the initiation and progression of cancer through a variety of mechanisms, including increased oxidative stress, immune suppression, and the activation of proliferative signaling pathways. This review aims to summarize current evidence from human studies and provide an overview of the potential mechanisms underscoring the role of chrononutrition (including time-restricted eating) on cancer risk. Current evidence shows that the morning chronotype, suggesting an alignment between physiological circadian rhythms and eating timing, is associated with a lower risk of cancer. Also, early time-restricted eating and prolonged nighttime fasting were also associated with a lower risk of cancer. The current evidence suggests that the chronotype influences cancer risk through cell cycle regulation, the modulation of metabolic pathways and inflammation, and gut microbiota fluctuations. In conclusion, although there are no clear guidelines on this matter, emerging evidence supports the hypothesis that the role of time-related eating (i.e., time/calorie-restricted feeding and intermittent/periodic fasting) could potentially lead to a reduced risk of cancer. metadata Godos, Justyna; Currenti, Walter; Ferri, Raffaele; Lanza, Giuseppe; Caraci, Filippo; Frias-Toral, Evelyn; Guglielmetti, Monica; Ferraris, Cinzia; Lipari, Vivian; Carvajal Altamiranda, Stefanía; Galvano, Fabio; Castellano, Sabrina y Grosso, Giuseppe mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, vivian.lipari@uneatlantico.es, stefania.carvajal@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR (2025) Chronotype and Cancer: Emerging Relation Between Chrononutrition and Oncology from Human Studies. Nutrients, 17 (3). p. 529. ISSN 2072-6643

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Artículos y libros
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica Abierto Inglés Background: Nut consumption has been considered a potential protective factor against cognitive decline. The aim of this study was to test whether higher total and specific nut intake was associated with better cognitive status in a sample of older Italian adults. Methods: A cross-sectional analysis on 883 older adults (>50 y) was conducted. A 110-item food frequency questionnaire was used to collect information on the consumption of various types of nuts. The Short Portable Mental Status Questionnaire was used to assess cognitive status. Multivariate logistic regression analyses were performed to calculate odds ratios (ORs) and 95% confidence intervals (CIs) for the association between nut intake and cognitive status after adjusting for potential confounding factors. Results: The median intake of total nuts was 11.7 g/day and served as a cut-off to categorize low and high consumers (mean intake 4.3 g/day vs. 39.7 g/day, respectively). Higher total nut intake was significantly associated with a lower prevalence of impaired cognitive status among older individuals (OR = 0.35, CI 95%: 0.15, 0.84) after adjusting for potential confounding factors. Notably, this association remained significant after additional adjustment for adherence to the Mediterranean dietary pattern as an indicator of diet quality, (OR = 0.32, CI 95%: 0.13, 0.77). No significant associations were found between cognitive status and specific types of nuts. Conclusions: Habitual nut intake is associated with better cognitive status in older adults. metadata Godos, Justyna; Giampieri, Francesca; Frias-Toral, Evelyn; Zambrano-Villacres, Raynier; Rojas Vistorte, Angel Olider; Yélamos Torres, Vanessa; Battino, Maurizio; Galvano, Fabio; Castellano, Sabrina y Grosso, Giuseppe mail SIN ESPECIFICAR, francesca.giampieri@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, angel.rojas@uneatlantico.es, vanessa.yelamos@funiber.org, maurizio.battino@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR (2025) Nut Consumption Is Associated with Cognitive Status in Southern Italian Adults. Nutrients, 17 (3). p. 521. ISSN 2072-6643

Artículo Materias > Biomedicina
Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Artículos y libros
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica Abierto Inglés Cardiovascular diseases (CVDs) are one of the main causes of mortality and morbidity worldwide. A healthy diet rich in plant-derived compounds such as (poly)phenols appears to have a key role in improving cardiovascular health. Flavan-3-ols represent a subclass of (poly)phenols of great interest for their possible health benefits. In this review, we summarized the results of clinical studies on vascular outcomes of flavan-3-ol supplementation and we focused on the role of the microbiota in CVD. Clinical trials included in this review showed that supplementation with flavan-3-ols mostly derived from cocoa products significantly reduces blood pressure and improves endothelial function. Studies on catechins from green tea demonstrated better results when involving healthy individuals. From a mechanistic point of view, emerging evidence suggests that microbial metabolites may play a role in the observed effects. Their function extends beyond the previous belief of ROS scavenging activity and encompasses a direct impact on gene expression and protein function. Although flavan-3-ols appear to have effects on cardiovascular health, further studies are needed to clarify and confirm these potential benefits and the rising evidence of the potential involvement of the microbiota. metadata Godos, Justyna; Romano, Giovanni Luca; Laudani, Samuele; Gozzo, Lucia; Guerrera, Ida; Dominguez Azpíroz, Irma; Martínez Díaz, Raquel; Quiles, José L.; Battino, Maurizio; Drago, Filippo; Giampieri, Francesca; Galvano, Fabio y Grosso, Giuseppe mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, irma.dominguez@unini.edu.mx, raquel.martinez@uneatlantico.es, jose.quiles@uneatlantico.es, maurizio.battino@uneatlantico.es, SIN ESPECIFICAR, francesca.giampieri@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR (2024) Flavan-3-ols and Vascular Health: Clinical Evidence and Mechanisms of Action. Nutrients, 16 (15). p. 2471. ISSN 2072-6643

Artículo Materias > Biomedicina Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Artículos y libros
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica Abierto Inglés Cardiovascular diseases are among the leading causes of mortality worldwide, with dietary factors being the main risk contributors. Diets rich in bioactive compounds, such as (poly)phenols, have been shown to potentially exert positive effects on vascular health. Among them, resveratrol has gained particular attention due to its potential antioxidant and anti-inflammatory action. Nevertheless, the results in humans are conflicting possibly due to interindividual different responses. The gut microbiota, a complex microbial community that inhabits the gastrointestinal tract, has been called out as potentially responsible for modulating the biological activities of phenolic metabolites in humans. The present review aims to summarize the main findings from clinical trials on the effects of resveratrol interventions on endothelial and vascular outcomes and review potential mechanisms interesting the role of gut microbiota on the metabolism of this molecule and its cardioprotective metabolites. The findings from randomized controlled trials show contrasting results on the effects of resveratrol supplementation and vascular biomarkers without dose-dependent effect. In particular, studies in which resveratrol was integrated using food sources, i.e., red wine, reported significant effects although the resveratrol content was, on average, much lower compared to tablet supplementation, while other studies with often extreme resveratrol supplementation resulted in null findings. The results from experimental studies suggest that resveratrol exerts cardioprotective effects through the modulation of various antioxidant, anti-inflammatory, and anti-hypertensive pathways, and microbiota composition. Recent studies on resveratrol-derived metabolites, such as piceatannol, have demonstrated its effects on biomarkers of vascular health. Moreover, resveratrol itself has been shown to improve the gut microbiota composition toward an anti-inflammatory profile. Considering the contrasting findings from clinical studies, future research exploring the bidirectional link between resveratrol metabolism and gut microbiota as well as the mediating effect of gut microbiota in resveratrol effect on cardiovascular health is warranted. metadata Godos, Justyna; Romano, Giovanni Luca; Gozzo, Lucia; Laudani, Samuele; Paladino, Nadia; Dominguez Azpíroz, Irma; Martínez López, Nohora Milena; Giampieri, Francesca; Quiles, José L.; Battino, Maurizio; Galvano, Fabio; Drago, Filippo y Grosso, Giuseppe mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, irma.dominguez@unini.edu.mx, nohora.martinez@uneatlantico.es, francesca.giampieri@uneatlantico.es, jose.quiles@uneatlantico.es, maurizio.battino@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR (2024) Resveratrol and vascular health: evidence from clinical studies and mechanisms of actions related to its metabolites produced by gut microbiota. Frontiers in Pharmacology, 15. ISSN 1663-9812

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Artículos y libros
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica Abierto Inglés Over the last decades, the Mediterranean diet gained enormous scientific, social, and commercial attention due to proven positive effects on health and undeniable taste that facilitated a widespread popularity. Researchers have investigated the role of Mediterranean-type dietary patterns on human health all around the world, reporting consistent findings concerning its benefits. However, what does truly define the Mediterranean diet? The myriad of dietary scores synthesizes the nutritional content of a Mediterranean-type diet, but a variety of aspects are generally unexplored when studying the adherence to this dietary pattern. Among dietary factors, the main characteristics of the Mediterranean diet, such as consumption of fruit and vegetables, olive oil, and cereals should be accompanied by other underrated features, such as the following: (i) specific reference to whole-grain consumption; (ii) considering the consumption of legumes, nuts, seeds, herbs and spices often untested when exploring the adherence to the Mediterranean diet; (iii) consumption of eggs and dairy products as common foods consumed in the Mediterranean region (irrespectively of the modern demonization of dietary fat intake). Another main feature of the Mediterranean diet includes (red) wine consumption, but more general patterns of alcohol intake are generally unmeasured, lacking specificity concerning the drinking occasion and intensity (i.e., alcohol drinking during meals). Among other underrated aspects, cooking methods are rather simple and yet extremely varied. Several underrated aspects are related to the quality of food consumed when the Mediterranean diet was first investigated: foods are locally produced, minimally processed, and preserved with more natural methods (i.e., fermentation), strongly connected with the territory with limited and controlled impact on the environment. Dietary habits are also associated with lifestyle behaviors, such as sleeping patterns, and social and cultural values, favoring commensality and frugality. In conclusion, it is rather reductive to consider the Mediterranean diet as just a pattern of food groups to be consumed decontextualized from the social and geographical background of Mediterranean culture. While the methodologies to study the Mediterranean diet have demonstrated to be useful up to date, a more holistic approach should be considered in future studies by considering the aforementioned underrated features and values to be potentially applied globally through the concept of a “Planeterranean” diet. metadata Godos, Justyna; Scazzina, Francesca; Paternò Castello, Corrado; Giampieri, Francesca; Quiles, José L.; Briones Urbano, Mercedes; Battino, Maurizio; Galvano, Fabio; Iacoviello, Licia; de Gaetano, Giovanni; Bonaccio, Marialaura y Grosso, Giuseppe mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, francesca.giampieri@uneatlantico.es, jose.quiles@uneatlantico.es, mercedes.briones@uneatlantico.es, maurizio.battino@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR (2024) Underrated aspects of a true Mediterranean diet: understanding traditional features for worldwide application of a “Planeterranean” diet. Journal of Translational Medicine, 22 (1). ISSN 1479-5876

Artículo Materias > Biomedicina
Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Artículos y libros
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica Abierto Inglés Isoflavones are a group of (poly)phenols, also defined as phytoestrogens, with chemical structures comparable with estrogen, that exert weak estrogenic effects. These phytochemical compounds have been targeted for their proven antioxidant and protective effects. Recognizing the increasing prevalence of cardiovascular diseases (CVD), there is a growing interest in understanding the potential cardiovascular benefits associated with these phytochemical compounds. Gut microbiota may play a key role in mediating the effects of isoflavones on vascular and endothelial functions, as it is directly implicated in isoflavones metabolism. The findings from randomized clinical trials indicate that isoflavone supplementation may exert putative effects on vascular biomarkers among healthy individuals, but not among patients affected by cardiometabolic disorders. These results might be explained by the enzymatic transformation to which isoflavones are subjected by the gut microbiota, suggesting that a diverse composition of the microbiota may determine the diverse bioavailability of these compounds. Specifically, the conversion of isoflavones in equol—a microbiota-derived metabolite—seems to differ between individuals. Further studies are needed to clarify the intricate molecular mechanisms behind these contrasting results. metadata Laudani, Samuele; Godos, Justyna; Romano, Giovanni Luca; Gozzo, Lucia; Di Domenico, Federica Martina; Dominguez Azpíroz, Irma; Martínez Díaz, Raquel; Giampieri, Francesca; Quiles, José L.; Battino, Maurizio; Drago, Filippo; Galvano, Fabio y Grosso, Giuseppe mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, irma.dominguez@unini.edu.mx, raquel.martinez@uneatlantico.es, francesca.giampieri@uneatlantico.es, jose.quiles@uneatlantico.es, maurizio.battino@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR (2024) Isoflavones Effects on Vascular and Endothelial Outcomes: How Is the Gut Microbiota Involved? Pharmaceuticals, 17 (2). p. 236. ISSN 1424-8247

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Artículos y libros
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica Abierto Inglés The prevalence of sleep disorders, characterized by issues with quality, timing, and sleep duration is increasing globally. Among modifiable risk factors, diet quality has been suggested to influence sleep features. The Mediterranean diet is considered a landmark dietary pattern in terms of quality and effects on human health. However, dietary habits characterized by this cultural heritage should also be considered in the context of overall lifestyle behaviors, including sleep habits. This study aimed to systematically revise the literature relating to adherence to the Mediterranean diet and sleep features in observational studies. The systematic review comprised 23 reports describing the relation between adherence to the Mediterranean diet and different sleep features, including sleep quality, sleep duration, daytime sleepiness, and insomnia symptoms. The majority of the included studies were conducted in the Mediterranean basin and reported a significant association between a higher adherence to the Mediterranean diet and a lower likelihood of having poor sleep quality, inadequate sleep duration, excessive daytime sleepiness or symptoms of insomnia. Interestingly, additional studies conducted outside the Mediterranean basin showed a relationship between the adoption of a Mediterranean-type diet and sleep quality, suggesting that biological mechanisms sustaining such an association may exist. In conclusion, current evidence suggests a relationship between adhering to the Mediterranean diet and overall sleep quality and different sleep parameters. The plausible bidirectional association should be further investigated to understand whether the promotion of a healthy diet could be used as a tool to improve sleep quality. metadata Godos, Justyna; Ferri, Raffaele; Lanza, Giuseppe; Caraci, Filippo; Rojas Vistorte, Angel Olider; Yélamos Torres, Vanessa; Grosso, Giuseppe y Castellano, Sabrina mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, angel.rojas@uneatlantico.es, vanessa.yelamos@funiber.org, SIN ESPECIFICAR, SIN ESPECIFICAR (2024) Mediterranean Diet and Sleep Features: A Systematic Review of Current Evidence. Nutrients, 16 (2). p. 282. ISSN 2072-6643