Documentos donde el Autor es "Castanedo Galán, Juan"

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Número de documentos: 8.

2024

Artículo Materias > Ingeniería Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Artículos y libros
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Abierto Inglés The IoT (Internet of Things) has played a promising role in e-healthcare applications during the last decade. Medical sensors record a variety of data and transmit them over the IoT network to facilitate remote patient monitoring. When a patient visits a hospital he may need to connect or disconnect medical devices from the medical healthcare system frequently. Also, multiple entities (e.g., doctors, medical staff, etc.) need access to patient data and require distinct sets of patient data. As a result of the dynamic nature of medical devices, medical users require frequent access to data, which raises complex security concerns. Granting access to a whole set of data creates privacy issues. Also, each of these medical user need to grant access rights to a specific set of medical data, which is quite a tedious task. In order to provide role-based access to medical users, this study proposes a blockchain-based framework for authenticating multiple entities based on the trust domain to reduce the administrative burden. This study is further validated by simulation on the infura blockchain using solidity and Python. The results demonstrate that role-based authorization and multi-entities authentication have been implemented and the owner of medical data can control access rights at any time and grant medical users easy access to a set of data in a healthcare system. The system has minimal latency compared to existing blockchain systems that lack multi-entity authentication and role-based authorization. metadata Alam, Shadab; Aslam, Muhammad Shehzad; Altaf, Ayesha; Iqbal, Faiza; Nigar, Natasha; Castanedo Galán, Juan; Gavilanes Aray, Daniel; Díez, Isabel de la Torre y Ashraf, Imran mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, juan.castanedo@uneatlantico.es, daniel.gavilanes@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR (2024) Novel model to authenticate role-based medical users for blockchain-based IoMT devices. PLOS ONE, 19 (7). e0304774. ISSN 1932-6203

2023

Artículo Materias > Ingeniería Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Artículos y libros
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Abierto Inglés Adaptive equalization is crucial in mitigating distortions and compensating for frequency response variations in communication systems. It aims to enhance signal quality by adjusting the characteristics of the received signal. Particle swarm optimization (PSO) algorithms have shown promise in optimizing the tap weights of the equalizer. However, there is a need to enhance the optimization capabilities of PSO further to improve the equalization performance. This paper provides a comprehensive study of the issues and challenges of adaptive filtering by comparing different variants of PSO and analyzing the performance by combining PSO with other optimization algorithms to achieve better convergence, accuracy, and adaptability. Traditional PSO algorithms often suffer from high computational complexity and slow convergence rates, limiting their effectiveness in solving complex optimization problems. To address these limitations, this paper proposes a set of techniques aimed at reducing the complexity and accelerating the convergence of PSO. metadata Khan, Arooj; Shafi, Imran; Khawaja, Sajid Gul; de la Torre Díez, Isabel; López Flores, Miguel Ángel; Castanedo Galán, Juan y Ashraf, Imran mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, miguelangel.lopez@uneatlantico.es, juan.castanedo@uneatlantico.es, SIN ESPECIFICAR (2023) Adaptive Filtering: Issues, Challenges, and Best-Fit Solutions Using Particle Swarm Optimization Variants. Sensors, 23 (18). p. 7710. ISSN 1424-8220

Artículo Materias > Ingeniería Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Artículos y libros
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Abierto Inglés Railway track faults may lead to railway accidents and cause human and financial loss. Spatial, temporal, and weather elements, and wear and tear, lead to ballast, loose nuts, misalignment, and cracks leading to accidents. Manual inspection of such defects is time-consuming and prone to errors. Automatic inspection provides a fast, reliable, and unbiased solution. However, highly accurate fault detection is challenging due to the lack of public datasets, noisy data, inefficient models, etc. To obtain better performance, this study presents a novel approach that relies on mel frequency cepstral coefficient features from acoustic data. The primary objective of this study is to increase fault detection performance. As well as designing an ensemble model, we utilize selective features using chi-square(chi2) that have high importance with respect to the target class. Extensive experiments were carried out to analyze the efficiency of the proposed approach. The experimental results suggest that using 60 features, 40 original features, and 20 chi2 features produces optimal results both regarding accuracy and computational complexity. A mean accuracy score of 0.99 was obtained using the proposed approach with machine learning models using the collected data. Moreover, this performance was significantly better than that of existing approaches; however, the performance of models may vary in real-world settings. metadata Rustam, Furqan; Ishaq, Abid; Hashmi, Muhammad Shadab Alam; Siddiqui, Hafeez Ur Rehman; Dzul Lopez, Luis; Castanedo Galán, Juan y Ashraf, Imran mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, luis.dzul@unini.edu.mx, juan.castanedo@uneatlantico.es, SIN ESPECIFICAR (2023) Railway Track Fault Detection Using Selective MFCC Features from Acoustic Data. Sensors, 23 (16). p. 7018. ISSN 1424-8220

Artículo Materias > Ingeniería Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Artículos y libros
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Abierto Inglés Disaster management is a critical area that requires efficient methods and techniques to address various challenges. This comprehensive assessment offers an in-depth overview of disaster management systems, methods, obstacles, and potential future paths. Specifically, it focuses on flood control, a significant and recurrent category of natural disasters. The analysis begins by exploring various types of natural catastrophes, including earthquakes, wildfires, and floods. It then delves into the different domains that collectively contribute to effective flood management. These domains encompass cutting-edge technologies such as big data analysis and cloud computing, providing scalable and reliable infrastructure for data storage, processing, and analysis. The study investigates the potential of the Internet of Things and sensor networks to gather real-time data from flood-prone areas, enhancing situational awareness and enabling prompt actions. Model-driven engineering is examined for its utility in developing and modeling flood scenarios, aiding in preparation and response planning. This study includes the Google Earth engine (GEE) and examines previous studies involving GEE. Moreover, we discuss remote sensing; remote sensing is undoubtedly a valuable tool for disaster management, and offers geographical data in various situations. We explore the application of Geographical Information System (GIS) and Spatial Data Management for visualizing and analyzing spatial data and facilitating informed decision-making and resource allocation during floods. In the final section, the focus shifts to the utilization of machine learning and data analytics in flood management. These methodologies offer predictive models and data-driven insights, enhancing early warning systems, risk assessment, and mitigation strategies. Through this in-depth analysis, the significance of incorporating these spheres into flood control procedures is highlighted, with the aim of improving disaster management techniques and enhancing resilience in flood-prone regions. The paper addresses existing challenges and provides future research directions, ultimately striving for a clearer and more coherent representation of disaster management techniques. metadata Khan, Saad Mazhar; Shafi, Imran; Butt, Wasi Haider; Diez, Isabel de la Torre; López Flores, Miguel Ángel; Castanedo Galán, Juan y Ashraf, Imran mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, miguelangel.lopez@uneatlantico.es, juan.castanedo@uneatlantico.es, SIN ESPECIFICAR (2023) A Systematic Review of Disaster Management Systems: Approaches, Challenges, and Future Directions. Land, 12 (8). p. 1514. ISSN 2073-445X

Artículo Materias > Ingeniería Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Artículos y libros
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Abierto Inglés The precise prediction of power estimates of wind–solar renewable energy sources becomes challenging due to their intermittent nature and difference in intensity between day and night. Machine-learning algorithms are non-linear mapping functions to approximate any given function from known input–output pairs and can be used for this purpose. This paper presents an artificial neural network (ANN)-based method to predict hybrid wind–solar resources and estimate power generation by correlating wind speed and solar radiation for real-time data. The proposed ANN allows optimization of the hybrid system’s operation by efficient wind and solar energy production estimation for a given set of weather conditions. The proposed model uses temperature, humidity, air pressure, solar radiation, optimum angle, and target values of known wind speeds, solar radiation, and optimum angle. A normalization function to narrow the error distribution and an iterative method with the Levenberg–Marquardt training function is used to reduce error. The experimental results show the effectiveness of the proposed approach against the existing wind, solar, or wind–solar estimation methods. It is envisaged that such an intelligent yet simplified method for predicting wind speed, solar radiation, and optimum angle, and designing wind–solar hybrid systems can improve the accuracy and efficiency of renewable energy generation. metadata Shafi, Imran; Khan, Harris; Farooq, Muhammad Siddique; Diez, Isabel de la Torre; Miró Vera, Yini Airet; Castanedo Galán, Juan y Ashraf, Imran mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, yini.miro@uneatlantico.es, juan.castanedo@uneatlantico.es, SIN ESPECIFICAR (2023) An Artificial Neural Network-Based Approach for Real-Time Hybrid Wind–Solar Resource Assessment and Power Estimation. Energies, 16 (10). p. 4171. ISSN 1996-1073

Artículo Materias > Ingeniería Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Artículos y libros
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Abierto Inglés Project-based organizations need to procure different commodities, and the failure/success of a project depends heavily on procurement management. Companies must refine and develop methods to simplify and optimize the procurement process in a highly competitive environment. This paper presents a methodology to help managers of project-based organizations analyze procurement processes to determine the optimal framework for simultaneously addressing multiple objectives. These goals include minimizing the time between the generation and required approval for a purchase, identifying unnamed activities, and allocating the budget efficiently. In this paper, we apply process mining algorithms to a dataset consisting of event logs on Oracle Financials-based enterprise resource planning (ERP) procurement processes in ERP systems and demonstrate interesting results leading to project procurement intelligence (PPI). The provided log data is the real-life data consisting of 180,462 events referring to seven activities within 43,101 cases. The logged procurement processes are filtered and analyzed using the open-source process mining frameworks PrOM and Disco. As a result of the process mining activities, a simulation of the discovered process model derived from the event log of the entire procurement process is presented, and the most frequent potential behaviors are identified. This analysis and extraction of frequent processes from corporate event logs help organizations understand, adapt, and redesign procurement operations and, most importantly, make them more efficient and of higher quality. This study shows that after the successful formulation of guiding principles, data refinement, and process structure optimization, the case study results are considered significant by the organization’s management. metadata Butt, Naveed Anwer; Mahmood, Zafar; Sana, Muhammad Usman; Díez, Isabel de la Torre; Castanedo Galán, Juan; Brie, Santiago y Ashraf, Imran mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, juan.castanedo@uneatlantico.es, santiago.brie@uneatlantico.es, SIN ESPECIFICAR (2023) Behavioral and Performance Analysis of a Real-Time Case Study Event Log: A Process Mining Approach. Applied Sciences, 13 (7). p. 4145. ISSN 2076-3417

Artículo Materias > Ingeniería Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Artículos y libros
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Abierto Inglés Traffic accidents present significant risks to human life, leading to a high number of fatalities and injuries. According to the World Health Organization’s 2022 worldwide status report on road safety, there were 27,582 deaths linked to traffic-related events, including 4448 fatalities at the collision scenes. Drunk driving is one of the leading causes contributing to the rising count of deadly accidents. Current methods to assess driver alcohol consumption are vulnerable to network risks, such as data corruption, identity theft, and man-in-the-middle attacks. In addition, these systems are subject to security restrictions that have been largely overlooked in earlier research focused on driver information. This study intends to develop a platform that combines the Internet of Things (IoT) with blockchain technology in order to address these concerns and improve the security of user data. In this work, we present a device- and blockchain-based dashboard solution for a centralized police monitoring account. The equipment is responsible for determining the driver’s impairment level by monitoring the driver’s blood alcohol concentration (BAC) and the stability of the vehicle. At predetermined times, integrated blockchain transactions are executed, transmitting data straight to the central police account. This eliminates the need for a central server, ensuring the immutability of data and the existence of blockchain transactions that are independent of any central authority. Our system delivers scalability, compatibility, and faster execution times by adopting this approach. Through comparative research, we have identified a significant increase in the need for security measures in relevant scenarios, highlighting the importance of our suggested model. metadata Farooq, Hamza; Altaf, Ayesha; Iqbal, Faiza; Castanedo Galán, Juan; Gavilanes Aray, Daniel y Ashraf, Imran mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, juan.castanedo@uneatlantico.es, daniel.gavilanes@uneatlantico.es, SIN ESPECIFICAR (2023) DrunkChain: Blockchain-Based IoT System for Preventing Drunk Driving-Related Traffic Accidents. Sensors, 23 (12). p. 5388. ISSN 1424-8220

Artículo Materias > Ingeniería Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Artículos y libros
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Abierto Inglés Society and the environment are severely impacted by catastrophic events, specifically floods. Inadequate emergency preparedness and response are frequently the result of the absence of a comprehensive plan for flood management. This article proposes a novel flood disaster management (FDM) system using the full lifecycle disaster event model (FLCNDEM), an abstract model based on the function super object. The proposed FDM system integrates data from existing flood protocols, languages, and patterns and analyzes viewing requests at various phases of an event to enhance preparedness and response. The construction of a task library and knowledge base to initialize FLCNDEM results in FLCDEM flooding response. The proposed FDM system improves the emergency response by offering a comprehensive framework for flood management, including pre-disaster planning, real-time monitoring, and post-disaster evaluation. The proposed system can be modified to accommodate various flood scenarios and enhance global flood management. metadata Khan, Saad Mazhar; Shafi, Imran; Butt, Wasi Haider; Díez, Isabel de la Torre; López Flores, Miguel Ángel; Castanedo Galán, Juan y Ashraf, Imran mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, miguelangel.lopez@uneatlantico.es, juan.castanedo@uneatlantico.es, SIN ESPECIFICAR (2023) Model Driven Approach for Efficient Flood Disaster Management with Meta Model Support. Land, 12 (8). p. 1538. ISSN 2073-445X

Este listado fue generado el Sun May 17 05:29:48 2026 UTC.

<a href="/28573/1/1-s2.0-S0033350626001848-main.pdf" class="ep_document_link"><img class="ep_doc_icon" alt="[img]" src="/style/images/fileicons/text.png" border="0"/></a>

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Association between socioeconomic and health variables and community-acquired pneumonia mortality rates in Chile from 1990 to 2021

Objectives To describe long-term trends in mortality attributed to community-acquired pneumonia (CAP) in Chile from 1990 to 2021, stratified by age group, and to evaluate associations with selected socioeconomic and demographic indicators. Study design Ecological, observational, longitudinal study using national secondary data. Methods CAP mortality rates were analyzed for the total population and by age group. Associations with the Human Development Index (HDI), poverty rate, aging index, and life expectancy at birth were examined using a hierarchical analytical approach. This included Spearman's rank correlation for initial exploration, multivariable linear regression to assess adjusted associations, and Prais–Winsten generalized least squares regression to account for first-order autocorrelation and shared temporal trends. Stationarity was evaluated using augmented Dickey–Fuller tests, with supplementary analyses using first-differenced variables. Missing data were imputed using time-based regression or interpolation, with sensitivity analyses performed. Results CAP mortality declined substantially across all age groups over the study period. Strong bivariate correlations were observed between mortality and all socioeconomic indicators; however, these associations were attenuated after adjustment for confounding and temporal autocorrelation. In multivariable and time-series models, HDI and the aging index remained significantly associated with CAP mortality in children (0–9 years) and older adults (≥65 years), whereas associations in intermediate age groups were not robust after accounting for shared secular trends. Poverty and life expectancy did not demonstrate independent associations in adjusted models. Conclusions CAP mortality in Chile has decreased markedly over the past three decades. Associations with socioeconomic indicators are strongest at the extremes of age and persist after accounting for temporal structure, although the ecological design precludes causal inference. These findings highlight the importance of considering demographic and socioeconomic context in population-level analyses of infectious disease outcomes.

Artículos y libros

Italo Salvador López Muñoz mail italo.lopez@doctorado.unini.edu.mx, Maria Loreto Romero Ladrón de Guevara mail , Christian R. Mejia mail , Shyla Del-Aguila-Arcentales mail , Aldo Alvarez-Risco mail , Neal M. Davies mail , Jaime A. Yáñez mail ,

López Muñoz

<a href="/28577/1/PIIS0002944026001367.pdf" class="ep_document_link"><img class="ep_doc_icon" alt="[img]" src="/style/images/fileicons/text.png" border="0"/></a>

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An Integrated Machine Learning and Genomic Framework for Precise Detection of Gastric Cancer

This study presents a novel integrative approach for the analysis of high-dimensional gene expression data, leveraging the complementary strengths of unsupervised clustering and supervised classification. Using K-means clustering, the dataset is stratified into three distinct clusters, revealing intrinsic biological patterns and relationships. The resulting cluster assignments are subsequently employed as pseudo-labels to train machine learning models, including support vector machines, random forest, and a stacking ensemble classifier. To validate and enhance the robustness of clustering, complementary methodologies such as hierarchical clustering and DBSCAN are employed, with results visualized through PCA-driven dimensionality reduction. The high predictive accuracy achieved by the classifiers underscores the separability and reliability of the identified clusters. Furthermore, feature importance analysis highlighted key genetic determinants within each cluster, offering actionable insights into potential biomarkers and critical genomic features. This framework bridges the gap between exploratory unsupervised learning and predictive supervised modeling, providing a scalable and interpretable methodology for analyzing complex genomic datasets. Its applicability extends to biomarker discovery, patient stratification, and other precision medicine applications, emphasizing its utility in advancing genomic research and clinical practice.

Producción Científica

Eshmal Iman mail , Sohail Jabbar mail , Shabana Ramzan mail , Ali Raza mail , Farwa Raoof mail , Stefanía Carvajal-Altamiranda mail stefania.carvajal@uneatlantico.es, Vivian Lipari mail vivian.lipari@uneatlantico.es, Imran Ashraf mail ,

Iman

<a href="/28319/1/s41598-026-45575-1_reference.pdf" class="ep_document_link"><img class="ep_doc_icon" alt="[img]" src="/style/images/fileicons/text.png" border="0"/></a>

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A novel approach for disease and pests detection in potato production system based on deep learning

Vulnerability of potato crops to diseases and pest infestation can affect its quality and lead to significant yield losses. Timely detection of such diseases can help take effective decisions. For this purpose, a deep learning-based object detection framework is designed in this study to identify and classify major potato diseases and pests under real-world field conditions. A total of 2,688 field images were collected from two research farms in Punjab, Pakistan, across multiple growth stages in various seasonal conditions. Excluding 285 symptoms-free images from the earliest collection led to 2,403 images which were annotated into four biotic-stress classes: blight disease (n = 630), leaf spot disease (n = 370), leafroll virus (viral symptom complex; n = 888), and Colorado potato beetle (larvae/adults; n = 515), indicating class imbalance. Several state-of-the-art models were used including YOLOv8 variants (n/s/m), YOLOv7, YOLOv5, and Faster R-CNN, and the results are discussed in relation to recent potato disease classification studies involving cropped leaf images. Stratified splitting (70% training, 20% validation, 10% testing) was applied to preserve class distribution across all subsets. YOLOv8-medium achieve the best performance with mean average precision (mAP)@0.5 of 98% on the held-out test images. Results for stable 5-fold cross-validation show a mean mAP@0.5 of 97.8%, which offers a balance between accuracy and inference time. Model robustness was evaluated using 5-fold cross-validation and repeated training with different random seeds, showing a low variance of ±0.4% mAP. Results demonstrate promising outcomes under the real-world field conditions, while, broader cross-region and cross-season validation is intended for the future.

Producción Científica

Ahmed Abbas mail , Saif Ur Rehman mail , Khalid Mahmood mail , Santos Gracia Villar mail santos.gracia@uneatlantico.es, Luis Alonso Dzul López mail luis.dzul@uneatlantico.es, Aseel Smerat mail , Imran Ashraf mail ,

Abbas

<a href="/28320/1/1-s2.0-S1876034126000912-main.pdf" class="ep_document_link"><img class="ep_doc_icon" alt="[img]" src="/style/images/fileicons/text.png" border="0"/></a>

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Concern for mpox infection in Latin America

Background Mpox arrived in Latin America and quickly began to replicate, so it is important to measure the concern it generates among residents. The study aims to assess whether country or other factors are associated with concern about mpox infection in Latin America. Methods The study uses a cross-sectional, multicenter design. Sampling was conducted using non-random snowball sampling. From August to September 2022, concern about being infected with mpox was assessed using a previously validated questionnaire (Cronbach's Alpha: 0.85); it was divided into nine countries and other social variables. Results From 1404 respondents, the majority of respondents were female (60.3%) and young (median age 25 years); also, a few reported that it was a significant problem (6% almost all the time and 11% often) and were concerned (6% almost all the time and 11% often) about the possibility of mpox infection. In multivariate analysis, men (aPR: 0.85; 95% CI: 0.73–0.99; p-value=0.046), younger (aPR: 0.98; 95% CI: 0.97–0.99; p-value<0.001), single (aPR: 0.78; 95% CI: 0.62–0.99; p-value=0.042) and, compared to Peru, those living in Colombia (aPR: 0.75; 95% CI. 0.58–0.97; p-value=0.027) and Costa Rica (aPR: 0.65; 95% CI: 0.44–0.96; p-value=0.032) reported the lowest concern; also, Bolivia (aPR: 1.16; 95% CI: 0.94–1.43; p-value=0.176) and Honduras (aPR: 1.01; 95% CI: 0.80–1.27; p-value=0.943) reported that their concerns tend to be higher. Conclusions There were evident differences across respondents' countries; these baseline results show that the first report was made in many countries that were also significantly affected by mpox and now face a new epidemic threatening public health.

Artículos y libros

Christian R. Mejia mail , Aldo Alvarez-Risco mail , Luciana Daniela Garlisi-Torales mail , Telmo Raúl Aveiro mail , Jamil Cedillo-Balcázar mail , Néstor Valentin Rocha-Saravia mail , Andrea Retana-González mail , Medally C. Paucar mail , Beatriz Mejia Raudales mail , Jose Armada mail , Shyla Del-Aguila-Arcentales mail , Neal M. Davies mail , Jaime A. Yáñez mail jaime.yanez@unini.edu.mx,

Mejia

<a class="ep_document_link" href="/28323/1/s40520-026-03363-x_reference.pdf"><img class="ep_doc_icon" alt="[img]" src="/style/images/fileicons/text.png" border="0"/></a>

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Fish consumption and brain structure: a comprehensive systematic review of observational studies

Background Age-related structural changes in the human brain, including cortical atrophy, reductions in grey and white matter volumes, and the accumulation of small vessel–related lesions such as white matter hyperintensities (WMH) and cerebral microbleeds, represent critical biological substrates underlying cognitive decline and dementia. Fish consumption has been associated with slower cognitive decline and reduced risk of dementia, but a comprehensive evaluation of its relation with brain structures is lacking. Aims The aim of this study was to systematically review current scientific literature providing evidence of relation between fish intake and brain structures in human studies. Methods Studies indexed in two major electronic databases have been screened based on a combination of keywords and MeSH terms. Studies were eligible whether they assessed fish consumption in relation to brain structures in the adult populations. Results A total of 24 studies conducted predominantly on older adults met inclusion criteria. Most brain volume measures were obtained via magnetic resonance imaging (MRI) procedures. Higher fish consumption was associated with reduced severity of white matter hyperintensities (a biomarker of cerebral small vessel disease and white matter damage) and cerebral micro-bleed, preservation of certain brain areas volumes (i.e., hippocampus, temporal lobe and periventricle white matter) and cortical thickness of specific areas (i.e., precuneus, parietal, and cingulate grey matter), among others, compared to lower intake. Some analyses found no association and isolated findings suggested possible adverse associations that were not consistently replicated. Studies reporting null findings may underline the possible relevance of the overall diet (i.e., adherence to the Mediterranean diet). Conclusions Inclusion of fish in a healthy and balanced diet is associated with better white matter grades on MRI and slower progression of white matter hyperintensities and reduction of vascular-related lesions of the aging brain, suggesting a potential role in preventing neurocognitive deterioration. Heterogeneity across studies underscores the need for additional studies.

Producción Científica

Justyna Godos mail , Giuseppe Caruso mail , Agnieszka Micek mail , Alberto Dolci mail , Zoltan Ungvari mail , Andrea Lehoczki mail , Lisandra León Brizuela mail , Evelyn Frias-Toral mail , Andrea Di Mauro mail , Mario Siervo mail , Michelino Di Rosa mail , Giuseppe Grosso mail ,

Godos